SYVN1 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Synovial apoptosis inhibitor 1, synoviolin

Gene Aliases

DER3, HRD1

Gene ID

84447

Swiss Prot

Q86TM6

Accession Number

NP_115807

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SYVN1

Target

SYVN1 is a protein involved in endoplasmic reticulum (ER) -associated degradation. The protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins.This gene encodes a protein involved in endoplasmic reticulum (ER) -associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms.

Partner Proteins

Rer1; OS9; SEL1L; STXBP5L; UBC; SYVN1; DERL2; HEY2; HEY1; USP19; Ube2g2; MARCH6; VCP; YOD1; ATXN3; DERL1; HERPUD1; TP53; BSG; ASGR1; GPR37; UBE2D3; UBE2D2; USP7; ATN1; APOB; ERLEC1; UBXN8; SHH; ERN1; ASGR2; SARAF; FAM8A1; TYR; AUP1; ERLIN2; SGK1; ATP6AP1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAA

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

67kDa

Protein Length

616

NCBI Gene Symbol

SYVN1

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase synoviolin

Gene Name URL

SYVN1

Nucleotide Accession Number

NM_032431

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