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PCGF6 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Polycomb group ring finger 6

Gene Aliases

MBLR, RNF134

Gene ID

84108

Swiss Prot

Q9BYE7-3

Accession Number

NP_115530

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PCGF6

Target

The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified.

Partner Proteins

EED; RNF2; CBX8; CBX7; CBX6; UBC; HSP90AA1; USP21; USP2; RING1; PEX10; BMI1; PCGF6; RAD18; WDR5; YAF2; TFDP1; MAX; HDAC1; E2F6; CBX3; L3MBTL2; RYBP; MGA; KDM5D; ELAVL1; SS18L1; UBE2U; CDK7

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TQPLYNISANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQ

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

30kDa

Protein Length

275

NCBI Gene Symbol

PCGF6

Host or Source

Rabbit

Protein Name

Polycomb group RING finger protein 6

Gene Name URL

PCGF6

Nucleotide Accession Number

NM_032154

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