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ITCH Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Itchy E3 ubiquitin protein ligase

Gene Aliases

AIF4, AIP4, ADMFD, NAPP1

Gene ID

83737

Swiss Prot

A9Z1X3

Accession Number

NP_113671

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ITCH

Target

Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like prot

Partner Proteins

GSN; UBE2L3; UBC; ITCH; WWOX; GGA3; UBE2D2; PTCH1; ATXN3; HTT; EGFR; SMAD6; DTX3L; CXCR4; LATS1; POLR2A; HNRNPL; EWSR1; RPAP2; CPSF7; RPAP3; UBAP2; PABPC1; DAZAP1; WBP2; SMARCE1; SMARCC2; SMARCC1; POLR2E; POLR2C; SPG20; HNRNPUL1; UBAP2L; URI1; ARID1A; SF1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QLESEVVTNGETTCSESASQNDDGSRSKDETRVSTNGSDDPEDAGAGENR

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 92%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

99kDa

Protein Length

862

NCBI Gene Symbol

ITCH

Host or Source

Rabbit

Gene Name URL

ITCH

Nucleotide Accession Number

NM_031483

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