UBE2E3 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Ubiquitin-conjugating enzyme E2E 3

Gene Aliases

UBCH9, UbcM2

Gene ID

10477

Swiss Prot

Q969T4

Accession Number

NP_006348

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2E3

Target

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Partner Proteins

RNF185; MUL1; TRIM39; RNF5; MID1; RNF25; MARCH5; UBE2E3; UBA1; TARDBP; UBC; HTT; ITCH; HERC4; NEDD4L; WWP2; RNF14; RNF8; MDM2; BRCA1; BARD1; KLHL42; RCBTB1; CUL1; CUL3; CUL4A; SPOP; ATXN1; ARID3A; RCBTB2; MOT2; CNOT4; NFE2L2; MID2; TRIM38; TRIM27; TRIM37

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERKPSATQQKKNTK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

23kDa

Protein Length

207

NCBI Gene Symbol

UBE2E3

Host or Source

Rabbit

Protein Name

Ubiquitin-conjugating enzyme E2 E3

Gene Name URL

UBE2E3

Nucleotide Accession Number

NM_006357

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-30359AF594 0.1 mL

Rabbit Polyclonal GAS2L3 Antibody [Alexa Fluor 594]

Ask

View Details

EK730613 96 Well

Mouse Collectin-10 (COLEC10) Elisa Kit

Ask

View Details