CDC23 antibody - N-terminal region (ARP43039_T100)

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Product Specifications

CAS Number

9007-83-4

Gene Name

Cell division cycle 23 homolog (S. cerevisiae)

Gene Aliases

APC8, CUT23, ANAPC8

Gene ID

8697

Swiss Prot

Q9UJX2

Accession Number

NP_004652

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CDC23

Target

CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Partner Proteins

CCDC36; DLX6-AS1; SPERT; KCTD6; FAM9B; CCDC24; SSX2IP; PNMA5; CRACR2A; LZTS2; ATRIP; INCA1; CEP44; SLC52A2; EIF5A2; BCAS3; CYB5R2; HEMK1; RSL24D1; RBM15B; ANAPC2; UBE2S; INPP5J; GORASP2; ANAPC13; RAD54B; RBPMS; OPTN; CDC23; APOL1; COIL; UBC; SOX5; SIAH1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEA

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

66kDa

Protein Length

597

NCBI Gene Symbol

CDC23

Host or Source

Rabbit

Protein Name

Cell division cycle protein 23 homolog

Gene Name URL

CDC23

Nucleotide Accession Number

NM_004661

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