RCHY1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase

Gene Aliases

ZCHY, ARNIP, CHIMP, PIRH2, RNF199, ZNF363, PRO1996

Gene ID

25898

Swiss Prot

Q96PM5

Accession Number

NP_001008925

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RCHY1

Target

RCHY1 has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53.The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms.

Partner Proteins

MEOX2; NOTCH2NL; UBASH3B; KRTAP9-2; LIMS2; SEMA4C; WDR74; ADAMTSL4; RCHY1; PGLS; KLHL41; MDM2; TAOK2; TP53; UBC; RNF2; HOXA2; YWHAE; CDK9; DCUN1D5; RILP; TMBIM1; CHD8; USP28; C19orf80; RBM38; NLK; TMEM14C; AIG1; SERTAD1; CHEK2; PRDX4; RAB11A; FADS6; TMEM1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KLYTCRLCHDNNEDHQLDRFKVKEVQCINCEKIQHAQQTCEECSTLFGEY

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

23kDa

Protein Length

200

NCBI Gene Symbol

RCHY1

Host or Source

Rabbit

Protein Name

RING finger and CHY zinc finger domain-containing protein 1

Gene Name URL

RCHY1

Nucleotide Accession Number

NM_001008925

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