Rag1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Recombination activating gene 1

Gene Aliases

Rag, Rag-1

Gene ID

19373

Swiss Prot

P15919

Accession Number

NP_033045

Reactivity

Mouse, Rat, Horse, Pig

Immunogen

The immunogen is a synthetic peptide corresponding to a region of Mouse

Target

As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V (D) J recombination. V (D) J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.

Partner Proteins

Gmeb1; Sf3a2; Kpna2; Rag1; UBE2C; UBE2H; UBE2E1; UBE2D2; UBE2D1; UBC; CDC34; Trav6-3; Rel; Nfkb1; Rela

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

IIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYT

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Horse: 100%; Mouse: 100%; Pig: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

119 kDa

Protein Length

1040

NCBI Gene Symbol

RAG1

Host or Source

Rabbit

Protein Name

V (D) J recombination-activating protein 1

Gene Name URL

Rag1

Nucleotide Accession Number

NM_009019

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RC212015L2V 200 µL

DISC1 (NM_018662) Human Tagged ORF Clone Lentiviral Particle

Ask

View Details

MBS8295347-01 10 nmol

hsa-miR-8073 miRNA Inhibitor

Ask

View Details

MBS8295347-02 20 nmol

hsa-miR-8073 miRNA Inhibitor

Ask

View Details

MBS8295347-03 5x 20 nmol

hsa-miR-8073 miRNA Inhibitor

Ask

View Details

TL514513 1 Kit

D830050J10Rik Mouse shRNA Plasmid (Locus ID 352968)

Ask

View Details

abx548357 96 Tests

Human T-complex protein 11-like protein 2 (TCP11L2) ELISA Kit

Ask

View Details