LIN7C Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Lin-7 homolog C (C. elegans)

Gene Aliases

MALS3, VELI3, LIN-7C, MALS-3, LIN-7-C

Gene ID

55327

Swiss Prot

Q9NUP9

Accession Number

NP_060832

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human LIN7C

Target

LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. It forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. LIN7C ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. It is also required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

Partner Proteins

UBC; AMOTL2; LATS2; YAP1; Wwtr1; CFTR; ELAVL1; AMOT; UIMC1; SPATA2; KCNJ12; BAIAP2; ABCA1; HTR2C; CASK; KCNJ4; DLG1; APBA1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAV

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

22kDa

Protein Length

197

NCBI Gene Symbol

LIN7C

Host or Source

Rabbit

Protein Name

Protein lin-7 homolog C

Gene Name URL

LIN7C

Nucleotide Accession Number

NM_018362

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

BT-AP00072-01 20 µL

AASD-PPT Polyclonal Antibody

Ask

View Details

BT-AP00072-02 50 µL

AASD-PPT Polyclonal Antibody

Ask

View Details

BT-AP00072-03 100 µL

AASD-PPT Polyclonal Antibody

Ask

View Details

P2140 200 mL/Kit

Goose Bone Marrow Neutrophil Isolation Solution Kit

Ask

View Details

EK342298 96 Well

Rat GDF2 (Growth Differentiation Factor 2) ValidElisa Kit

Ask

View Details

MC218191 10 µg

Il18r1 (NM_008365) Mouse Untagged Clone

Ask

View Details