PARD6A antibody - N-terminal region (ARP42883_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Par-6 partitioning defective 6 homolog alpha (C. elegans)

Gene Aliases

PAR6, PAR6C, TAX40, PAR-6A, TIP-40, PAR6alpha

Gene ID

50855

Swiss Prot

Q3TY70

Accession Number

NP_001032358

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PARD6A

Target

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

PRKCI; WDR83; PRKCZ; FBXO31; PARD3; UBC; TUBG1; ARHGAP17; VHL; MAP2K5; TJP1; SMURF1; TGFB1; WDR92; PARD6B; PDRG1; RPAP3; MARK4; PIH1D1; SUGT1; YWHAZ; YWHAH; LLGL1; LLGL2; MARK2; CDC42; CRB3; ECT2; PLCB1; RHOQ; PRKCH; RAC1; CDH5; PLCB3; TGFBR1; TCP10; PRKC

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MARPQRTPARSPDSIVEVKSKFDAEFRRFALPRASVSGFQEFSRLLRAVH

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

37kDa

Protein Length

345

NCBI Gene Symbol

PARD6A

Host or Source

Rabbit

Protein Name

Putative uncharacterized protein EMBL BAE34693.1

Gene Name URL

PARD6A

Nucleotide Accession Number

NM_001037281

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