KRT1 antibody - middle region (ARP42278_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Keratin 1
Gene Aliases
K1, CK1, EHK, EHK1, EPPK, KRT1A, NEPPK
Gene ID
3848
Swiss Prot
P04264
Accession Number
NP_006112
Reactivity
Human, Rat, Dog, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human KRT1
Target
KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
MDM2; LGR4; EED; ESR1; ADRB2; PAN2; Iqcb1; Nphp4; Cep290; Nphp1; Invs; GRDX; VCAM1; UBC; ITGA4; FN1; CDH1; APOA1; ALB; MAGOH; EIF4A3; KRT10; KRT9; KRT2; SLC25A5; SHC1; PIK3R2; INPPL1; GRB2; EPS15; CRK; AP2M1; CBL; UBASH3B; NEDD8; CAND1; DCUN1D1; COPS5; CO
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
GSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKS
Applications
IHC, WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Dog: 86%; Human: 100%; Rabbit: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
66kDa
Protein Length
644
NCBI Gene Symbol
KRT1
Host or Source
Rabbit
Protein Name
Keratin, type II cytoskeletal 1
Gene Name URL
KRT1
Nucleotide Accession Number
NM_006121
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