ATP2A1 Antibody - middle region

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Product Specifications

CAS Number

9007-83-4

Gene Name

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

Gene Aliases

ATP2A, SERCA1

Gene ID

487

Swiss Prot

O14983

Accession Number

NP_004311

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ATP2A1

Target

This gene encodes one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.

Partner Proteins

UBC; LGR4; WWOX; CFTR; ITPR3; CUL3; PCK1; SLN; IRS2; PLN; IRS1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

IFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEY

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

110 kDa

Protein Length

1001

NCBI Gene Symbol

ATP2A1

Host or Source

Rabbit

Protein Name

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

Gene Name URL

ATP2A1

Nucleotide Accession Number

NM_001286075.1

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