MAP3K14 antibody - N-terminal region (ARP42161_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Mitogen-activated protein kinase kinase kinase 14

Gene Aliases

HS, NIK, HSNIK, FTDCR1B

Gene ID

9020

Swiss Prot

Q99558

Accession Number

NP_003945

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K14

Target

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

Partner Proteins

UBC; TRAF3; TRAF2; BIRC2; TRAF1; IKBKB; HSP90AA1; CHUK; TRAF6; TNAP; PELI3; TRAF5; TANK; NFKB2; ARRB2; ZFP91; EEF1A1; PEBP1; HSP90AB1; CDC37; MAP3K14; EDAR; IKBKAP; RPL6; RPL5; RIPK1; MAP3K7; MAPK3; CASP8; GRB14; GRB10; GRB7; MAP2K4; IKBKG; MAP3K8; RPL4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SEAGPAAISIIAQAECENSQEFSPTFSERIFIAGSKQYSQSESLDQIPNN

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

104kDa

Protein Length

947

NCBI Gene Symbol

MAP3K14

Host or Source

Rabbit

Protein Name

Mitogen-activated protein kinase kinase kinase 14

Gene Name URL

MAP3K14

Nucleotide Accession Number

NM_003954

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