F2 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Coagulation factor II (thrombin)

Gene Aliases

PT, THPH1, RPRGL2

Gene ID

2147

Swiss Prot

P00734

Accession Number

NP_000497

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human F2

Target

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life.Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

ST13; FN1; DDIT3; ALB; F11; PROZ; ITGA2B; SERPING1; HGFAC; AKR7A2; CPB2; F2RL3; F2RL2; SERPINA5; SERPINB8; AANAT; F2RL1; F9; F8; GP1BA; KNG1; F5; C6; PLAU; THBS1; THBD; F2R; SERPINE2; F2; PROS1; AMBP; PROC; GP5; SERPINE1; SERPINB6; SPP1; IGFBP5; IGFBP3; S

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLE

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol