STK11 antibody - N-terminal region (ARP41743_T100)

Product Specifications

CAS Number

9007-83-4

Gene Name

Serine/threonine kinase 11

Gene Aliases

PJS, LKB1, hLKB1

Gene ID

6794

Swiss Prot

Q15831

Accession Number

NP_000446

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human STK11

Target

STK11is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in its gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Partner Proteins

SPDEF; SIRT1; PRKAA1; ETV4; CDC37; HSP90AA1; TP63; Eif2b1; Ap2m1; SNRK; APP; TNIP2; SIK1; STRADA; STUB1; UBE2D2; MARK2; GSK3B; STRADB; CAB39; KIF23; USP11; SMARCC1; SMARCA4; LIMS1; HSPA1A; FKBP5; RPAP3; MARK4; UBC; CAB39L; WDR48; RPS6KB1; MOB4; MARK1; RPS

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNE

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol