D-Panthenol

D-Panthenol is the biologically-active alcohol of pantothenic acid, which leads to an elevation in the amount of coenzyme A in the cell. D-panthenol exhibits nephroprotective effect in AKI, promotes tissue repair and regeneration.

Product Specifications

CAS Number

[81-13-0]

Product Name Alternative

Dexpanthenol

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/D-Panthenol.html

Purity

99.98

Solubility

DMSO : 200 mg/mL (ultrasonic) |Ethanol : 110 mg/mL (ultrasonic)

Smiles

O=C([C@@H](C(C)(CO)C)O)NCCCO

Molecular Formula

C9H19NO4

Molecular Weight

205.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Oguz A, et al. Topical N-acetylcysteine improves wound healing comparable to dexpanthenol: an experimental study. Int Surg. 2015 Apr;100 (4) :656-61.|[2]Semenovich DS, et al., Protective Effect of D-Panthenol in Rhabdomyolysis-Induced Acute Kidney Injury. Int J Mol Sci. 2022 Oct 14;23 (20) :12273.|[3]linova E, et al., Cerium-Containing N-Acetyl-6-Aminohexanoic Acid Formulation Accelerates Wound Reparation in Diabetic Animals. Biomolecules. 2021 Jun 3;11 (6) :834.|[4]Semenovich DS, et al., Effects of Panthenol and N-Acetylcysteine on Changes in the Redox State of Brain Mitochondria under Oxidative Stress In Vitro. Antioxidants (Basel) . 2021 Oct 27;10 (11) :1699.