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LPPRC Antibody - N-terminal region (ARP41093_P050)

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Product Specifications

CAS Number

9007-83-4

Gene Name

Leucine rich pentatricopeptide repeat containing

Gene Aliases

LSFC, GP130, LRP130, MC4DN5, CLONE-23970

Gene ID

10128

Swiss Prot

P42704

Accession Number

NP_573566

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human LPPRC

Target

This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR) . The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.

Partner Proteins

SPRTN; CEP76; HAUS2; CEP250; SART3; AURKB; TP53; AURKA; SUMO2; SUMO3; CDKN1A; IVNS1ABP; STAU1; UBC; MDM2; LGR4; ASB5; RNF2; EZH2; BMI1; PARK2; FBXO6; ADRB2; METTL22; vpu; ITGA4; FN1; C1QBP; VCAM1; PEX14; SMURF1; ILF3; CPS1; MRPS35; SEC23A; GRK5; UBD; CDK2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NEYKFSPTDFLAKMEEANIQPNRVTYQRLIASYCNVGDIEGASKILGFMK

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

153kDa

Protein Length

1394

NCBI Gene Symbol

LRPPRC

Host or Source

Rabbit

Protein Name

Leucine-rich PPR motif-containing protein, mitochondrial

Gene Name URL

LRPPRC

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