FIP1L1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

FIP1 like 1 (S. cerevisiae)

Gene Aliases

Rhe, FIP1, hFip1

Gene ID

81608

Swiss Prot

Q6UN15

Accession Number

NP_112179

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human FIP1L1

Target

FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. FIP1L1 contributes to poly (A) site recognition and stimulates poly (A) addition. It binds to U-rich RNA sequence elements surrounding the poly (A) site. FIP1L1 may act to tether poly (A) polymerase to the CPSF complex.

Partner Proteins

ZMYND19; CPSF4; NAA10; SGTA; GOLGA2; STAU1; UBC; WWOX; SUZ12; RNF2; EZH2; PRMT6; PRMT2; CLK2; HDAC9; CSNK2A1; LIG4; WDR33; CPSF2; CPSF3; CPSF1; NUP153; APP; COPS5; HNRNPA1; SRRM2; RNPS1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGD

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

65kDa

Protein Length

594

NCBI Gene Symbol

FIP1L1

Host or Source

Rabbit

Protein Name

Pre-mRNA 3'-end-processing factor FIP1

Gene Name URL

FIP1L1

Nucleotide Accession Number

NM_030917

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