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UPF3A antibody - middle region (ARP41000_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

UPF3 regulator of nonsense transcripts homolog A (yeast)

Gene Aliases

UPF3, HUPF3A, RENT3A

Gene ID

65110

Swiss Prot

Q9H1J1

Accession Number

NP_075387

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human UPF3A

Target

UPF3A is part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. UPF3A is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Binds spliced mRNA upstream of exon-exon j

Partner Proteins

HTT; SMG1; HBB; APP; RNPS1; NXF1; SRRM1; TOPORS; PIGT; ALYREF; IFITM2; RBM8A; GSK3B; UPF1; UPF2; DCP2; UPF3B; EXOSC4; XRN1; EXOSC2; EXOSC10; PARN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QRYHVDDGRRHRAHHEPERLSRRSEDEQRWGKGPGQDRGKKGSQDSGAPG

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

55kDa

Protein Length

476

NCBI Gene Symbol

UPF3A

Host or Source

Rabbit

Protein Name

Regulator of nonsense transcripts 3A

Gene Name URL

UPF3A

Nucleotide Accession Number

NM_023011

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