DGCR8 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

DiGeorge syndrome critical region gene 8

Gene Aliases

Gy1, pasha, DGCRK6, C22orf12

Gene ID

54487

Swiss Prot

Q8WYQ5

Accession Number

NP_073557

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DGCR8

Target

DGCR8 contains 2 DRBM (double-stranded RNA-binding) domains and 1 WW domain. It may play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies.

Partner Proteins

MEOX2; PYCRL; DROSHA; RAE1; MAPK1; PRMT1; ERH; CDKN2A; BMI1; SRPK2; SRPK1; CDT1; NAT10; PLEK2; RPRD2; MAPRE2; PRPF4; FLII; APP; CUL3; DDX17; HNRNPR; NCL; ILF3; HSPA8; HSPA5; HNRNPU; HNRNPH1; FUS; DHX9; DDX5

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

DKKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDR

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

86 kDa

Protein Length

773

NCBI Gene Symbol

DGCR8

Host or Source

Rabbit

Protein Name

Microprocessor complex subunit DGCR8

Gene Name URL

DGCR8

Nucleotide Accession Number

NM_022720

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS670578-01 1 mg

Goat Anti-Human IgG (H+L), Multi-Species SP ads-BIOT

Ask

View Details

MBS670578-02 5x 1 mg

Goat Anti-Human IgG (H+L), Multi-Species SP ads-BIOT

Ask

View Details

MBS1064461-01 0.02 mg (E-Coli)

Recombinant Cyanothece sp. Deoxyribose-phosphate aldolase (deoC)

Ask

View Details

MBS1064461-02 0.1 mg (E-Coli)

Recombinant Cyanothece sp. Deoxyribose-phosphate aldolase (deoC)

Ask

View Details

MBS1064461-03 0.02 mg (Yeast)

Recombinant Cyanothece sp. Deoxyribose-phosphate aldolase (deoC)

Ask

View Details

MBS1064461-04 0.1 mg (Yeast)

Recombinant Cyanothece sp. Deoxyribose-phosphate aldolase (deoC)

Ask

View Details