XRN1 antibody - middle region (ARP40931_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

5'-3' exoribonuclease 1

Gene Aliases

45536

Gene ID

54464

Swiss Prot

Q8IZH2

Accession Number

NP_061874

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human XRN1

Target

SEP1 (XRN1) localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-67 BX640905.1 1-67 68-5188 AY137776.1 1-5121 5189-5269 BG197321.1 308-388 5270-10092 AC023508.16 31718-36540 c

Partner Proteins

ZFP36; UBC; RPA3; RPA2; RPA1; BMI1; HECW2; HERC2P4; RNF187; B3GALT6; EXOSC6; C1orf85; VWA5B2; MFSD5; PRADC1; ANGPTL6; PLEKHG2; SPATA20; C1GALT1; DCP1A; HEATR1; NDUFA13; EXOSC1; DPP7; RBMX; MTCH2; TMEM50A; CD97; ATP5G2; SNHG1; LINC01541; DCP1B; SRRM2; SKIV

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKM

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 93%; Guinea Pig: 79%; Horse: 90%; Human: 100%; Mouse: 86%; Pig: 85%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

194 kDa

Protein Length

1706

NCBI Gene Symbol

XRN1

Host or Source

Rabbit

Protein Name

5'-3' exoribonuclease 1

Gene Name URL

XRN1

Nucleotide Accession Number

NM_019001

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