A2BP1 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

RNA binding protein, fox-1 homolog (C. elegans) 1

Gene Aliases

2BP1, FOX1, A2BP1, FOX-1, HRNBP1

Gene ID

54715

Swiss Prot

Q9NWB1

Accession Number

NP_061193

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human A2BP1

Target

Ataxin-2 binding protein 1 (A2BP1) has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2) . Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.

Partner Proteins

C1orf94; RBPMS; PRR20A; HSFY1; RHOXF2; ALG13; RBFOX1; FAM168A; DAZAP2; MAGED1; BHLHE40; SNRPN; DAB1; CRX; UBC; HSFX1; RBM24; LZTS2; DMRTB1; PCBP4; NOC2L; GCA; RBFOX2; KIFAP3; CELF3; PSMF1; QKI; NUMBL; PRRC2A; ATXN2; ATXN1; HNRNPF; DVL2; ATN1; TNIP1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRD

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

43kDa

Protein Length

397

NCBI Gene Symbol

RBFOX1

Host or Source

Rabbit

Protein Name

RNA binding protein fox-1 homolog 1

Gene Name URL

RBFOX1

Nucleotide Accession Number

NM_018723

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