CPSF2 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Cleavage and polyadenylation specific factor 2, 100kDa

Gene Aliases

CPSF100

Gene ID

53981

Swiss Prot

Q9P2I0

Accession Number

NP_059133

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CPSF2

Target

CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. It belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily.

Partner Proteins

RBBP6; UBC; WWOX; EZH2; rev; HECW2; CLK2; NPM1; CPSF3; SYMPK; CSTF2; MDC1; ECT2; BARD1; GTF3C6; FIP1L1; WDR33; POLE3; CPSF1; RALBP1; MED17; GTF3C3; SMARCD3; SMARCA4; POLR2A; CUL3; HNRNPA1; ELAVL1; SUMO2; SMARCAD1; CSTF2T; RRAGA; TBP; PSMA3; CLP1; CDC73; R

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

YAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAA

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

88kDa

Protein Length

782

NCBI Gene Symbol

CPSF2

Host or Source

Rabbit

Protein Name

Cleavage and polyadenylation specificity factor subunit 2

Gene Name URL

CPSF2

Nucleotide Accession Number

NM_017437

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