CPSF3 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Cleavage and polyadenylation specific factor 3, 73kDa

Gene Aliases

CPSF73, CPSF-73

Gene ID

51692

Swiss Prot

Q9UKF6

Accession Number

NP_057291

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CPSF3

Target

CPSF3 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily. It is component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition.

Partner Proteins

UBC; SUMO1; WWOX; AICDA; POLR2A; NPM1; TUT1; SYMPK; CSTF2; CPSF2; PAXIP1; MDC1; BARD1; FIP1L1; POLR1E; WDR33; CPSF1; UBD; SIRT7; SMARCAD1; RRAGA; TBP; CDC73; CLP1; PAPOLA; YWHAG

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

DDSILSVTVDGKTANLNLETRTVECEEGSEDDESLREMVELAAQRLYEAL

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

75kDa

Protein Length

684

NCBI Gene Symbol

CPSF3

Host or Source

Rabbit

Protein Name

Cleavage and polyadenylation specificity factor subunit 3

Gene Name URL

CPSF3

Nucleotide Accession Number

NM_016207

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