SF3B6 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Splicing factor 3b subunit 6

Gene Aliases

P14, Ht006, SAP14, SAP14a, SF3B14, CGI-110, HSPC175, SF3B14a

Gene ID

51639

Swiss Prot

Q7RTV0

Accession Number

NP_057131

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SF3B14

Target

This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.

Partner Proteins

UBC; WWOX; SUZ12; EED; PAN2; ITGA4; FN1; SF3B1; VCAM1; SF3B5; THOC6; WDR18; TRA2A; PRPF19; RBMX; SF3B3; PUF60; DHX15; RCC1; APP; U2AF2; ZNF326; ZC3H18; FTSJ3; PHF5A; TRIM55; SF3B2; UTP14A; USP39; PRPF8; BCAS2; SF3B4; THRAP3; EFTUD2; SRSF11; SART1; VTN; U2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

HLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKYGINTDPPK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

14kDa

Protein Length

125

NCBI Gene Symbol

SF3B6

Host or Source

Rabbit

Protein Name

Splicing factor 3B subunit 6

Gene Name URL

SF3B6

Nucleotide Accession Number

NM_016047

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