PUF60 Antibody - C-terminal region

Click here to learn more about Aviva's By-Request Conjugation Service.//here

Product Specifications

CAS Number

9007-83-4

Gene Name

Poly-U binding splicing factor 60KDa

Gene Aliases

FIR, VRJS, RoBPI, SIAHBP1

Gene ID

22827

Swiss Prot

Q9UHX1-2

Accession Number

NP_055096

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PUF60

Target

PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.

Partner Proteins

ZG16; ARL8A; LOH12CR1; KIAA1683; MED28; QRICH1; UBE2I; SIAH1; SRSF11; SAP30BP; UPF2; KIAA0907; PUF60; U2AF2; SDCBP; RAD23B; CCNC; SUMO2; SUMO3; CDKN1A; UBC; ERG; EED; H3F3A; FAM129B; VPS29; FAF1; PAPOLA; NUDC; HIRIP3; ZYX; UGP2; TARS; TROVE2; PPM1G; PPP1R

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

58kDa

Protein Length

542

NCBI Gene Symbol

PUF60

Host or Source

Rabbit

Protein Name

Poly (U) -binding-splicing factor PUF60

Gene Name URL

PUF60

Nucleotide Accession Number

NM_014281

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

CMH0766-01 5 nmol

Hsa-miR-1303 miRNA Mimic

Ask

View Details

CMH0766-02 10 nmol

Hsa-miR-1303 miRNA Mimic

Ask

View Details

MBS744604-01 48 Well

Rabbit Complement component 5b ELISA Kit

Ask

View Details

MBS744604-02 96 Well

Rabbit Complement component 5b ELISA Kit

Ask

View Details

MBS744604-03 5x 96 Well

Rabbit Complement component 5b ELISA Kit

Ask

View Details

MBS744604-04 10x 96 Well

Rabbit Complement component 5b ELISA Kit

Ask

View Details