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CPSF1 antibody - middle region (ARP40741_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Cleavage and polyadenylation specific factor 1, 160kDa

Gene Aliases

MYP27, CPSF160, P/cl.18, HSU37012

Gene ID

29894

Swiss Prot

Q10570

Accession Number

NP_037423

Reactivity

Human, Rat, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CPSF1

Target

CPSF1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.

Partner Proteins

REL; RBBP6; UBC; STAU1; LGR4; WWOX; RPA3; RPA2; RPA1; EED; EZH2; NEDD4; TARDBP; ICK; CLK2; HDAC6; NPM1; IL7R; HMOX1; TUT1; FIP1L1; RNPC3; WDR33; CPSF2; MED8; CPSF3; GTF3C3; POLR2A; COPS6; CUL3; SIRT7; SMARCAD1; CSTF2T; PAPOLA; CSTF3; GLIS2; RRAGA; TBP; TA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GCYDMWTVIAPVRKEEEDNPKGEGTEQEPSTTPEADDDGRRHGFLILSRE

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Horse: 79%; Human: 100%; Rat: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

161kDa

Protein Length

1443

NCBI Gene Symbol

CPSF1

Host or Source

Rabbit

Protein Name

Cleavage and polyadenylation specificity factor subunit 1

Gene Name URL

CPSF1

Nucleotide Accession Number

NM_013291

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