CPSF6 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Cleavage and polyadenylation specific factor 6, 68kDa

Gene Aliases

CFIM, CFIM68, CFIM72, HPBRII-4, HPBRII-7

Gene ID

11052

Swiss Prot

Q16630

Accession Number

NP_008938

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CPSF6

Target

CPSF6 is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides.The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.

Partner Proteins

ARMC7; OTUB2; TOLLIP; PPIL1; FUS; FXR2; WWOX; EZH2; SUZ12; EED; rev; ITCH; PRPF40A; WBP4; TCERG1; NEDD4; APBB1; SRPK2; WWP1; NUDT21; LMNA; CD81; TP63; UBC; NPM1; FN1; DAB2; CSNK2A1; SMURF1; BARD1; MDC1; ZBTB8B; CPSF7; NUP107; TBC1D2; WBP11; PUF60; U2AF2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPP

Applications

IF, IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

61kDa

Protein Length

551

NCBI Gene Symbol

CPSF6

Host or Source

Rabbit

Protein Name

Cleavage and polyadenylation specificity factor subunit 6

Gene Name URL

CPSF6

Nucleotide Accession Number

NM_007007

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