KHDRBS1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

KH domain containing, RNA binding, signal transduction associated 1

Gene Aliases

P62, p68, Sam68

Gene ID

10657

Swiss Prot

Q07666

Accession Number

NP_006550

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human KHDRBS1

Target

KHDRBS1 recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, KHDRBS1 functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. KHDRBS1 play a role in G2-M progression in the cell cycle. It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. KHDRBS1 also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.

Partner Proteins

UBC; LGR4; DROSHA; RPA3; RPA2; RPA1; RNF2; EZH2; BMI1; SUZ12; rev; APBB1; GAS7; WBP4; RASA1; SRC; CSK; PLCG1; PIK3R1; IRS1; CD81; TNFRSF1A; KHDRBS3; GPHN; RBM7; PIK3R3; HNRNPK; GRB2; EFEMP1; DHX9; DDX5; CRKL; CIRBP; ACTB; AZIN1; RBMX; AGO1; POT1; RBFOX2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LPELMAEKDSLDPSFTHAMQLLTAEIEKIQKGDSKKDDEENYLDLFSHKN

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

48kDa

Protein Length

443

NCBI Gene Symbol

KHDRBS1

Host or Source

Rabbit

Protein Name

KH domain-containing, RNA-binding, signal transduction-associated protein 1

Gene Name URL

KHDRBS1

Nucleotide Accession Number

NM_006559

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP3-00324AF647 0.1 mL

Rabbit Polyclonal ECH1 Antibody [Alexa Fluor 647]

Ask

View Details

TS420920P5 25 Slides

NRP2 CytoSection

Ask

View Details

MBS9441614-01 0.1 mL (Biotin)

SOS1 Polyclonal Conjugated Antibody

Ask

View Details

MBS9441614-02 0.1 mL (AF350)

SOS1 Polyclonal Conjugated Antibody

Ask

View Details

MBS9441614-03 0.1 mL (AF405)

SOS1 Polyclonal Conjugated Antibody

Ask

View Details

MBS9441614-04 0.1 mL (AF488)

SOS1 Polyclonal Conjugated Antibody

Ask

View Details