KHDRBS3 antibody - C-terminal region (ARP40663_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

KH domain containing, RNA binding, signal transduction associated 3

Gene Aliases

Etle, SALP, SLM2, SLM-2, TSTAR, T-STAR, etoile

Gene ID

10656

Swiss Prot

O75525

Accession Number

NP_006549

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human KHDRBS3

Target

As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.

Partner Proteins

YTHDC1; DMRT3; MARK4; NCOA5; PRPF31; BAHD1; KHDRBS3; INPP5D; UBC; BMI1; NELFB; RBM7; PSMF1; SIAH1; HNRNPK; KHDRBS2; CCDC33; PTBP2; U2AF2; KHDRBS1; SNRPC; HNRNPC; FUS; FBXO32; SERPINB5; RBBP6; CACNA1A; RPAP2; ZNF408; LNX1; SGSM2; SRSF9; NUDT18; PRMT1; RBMY

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPS

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

38kDa

Protein Length

346

NCBI Gene Symbol

KHDRBS3

Host or Source

Rabbit

Protein Name

KH domain-containing, RNA-binding, signal transduction-associated protein 3

Gene Name URL

KHDRBS3

Nucleotide Accession Number

NM_006558

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