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SNUPN Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Snurportin 1

Gene Aliases

KPNBL, RNUT1, Snurportin1

Gene ID

10073

Swiss Prot

O95149

Accession Number

NP_005692

Reactivity

Human, Mouse, Rat, Cow, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SNUPN

Target

The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

Partner Proteins

UBC; HOTAIR; MEX3B; XPO1; GCNT3; RNF126; DBN1; RPL17; KPNB1; PAFAH1B2; TNNT3; PEX5; ENO2; RAN; DDX20; ZPR1; SNRPB; SMN1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GVAVPAGPLTTKPDYAGHQLQQIMEHKKSQKEGMKEKLTHKASENGHYEL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 85%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

41kDa

Protein Length

360

NCBI Gene Symbol

SNUPN

Host or Source

Rabbit

Protein Name

Snurportin-1

Gene Name URL

SNUPN

Nucleotide Accession Number

NM_005701

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