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SCYE1 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

Gene Aliases

P43, HLD3, EMAP2, SCYE1, EMAPII

Gene ID

9255

Swiss Prot

Q12904

Accession Number

NP_004748

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SCYE1

Target

SCYE1 is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells. The protein encoded by this gene is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

AIMP2; TSNAX; UBC; CCAR2; RPL36; EEF1E1; IQGAP1; VARS; RPLP0; RPL27A; RPL23A; RPL21; RPL17; RPL15; RPL13; RPL7A; RARS; QARS; PTBP1; PSMC6; MARS; KARS; IARS; DNAJA1; EIF4G1; EIF2S3; EIF2S1; DARS; PAN2; gag; HSP90B1; MAPK8; LARS; EPRS; APP; COPS5; CUL1; PSM

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 100%; Rat: 93%; Yeast: 86%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

34kDa

Protein Length

312

NCBI Gene Symbol

AIMP1

Host or Source

Rabbit

Protein Name

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

Gene Name URL

AIMP1

Nucleotide Accession Number

NM_004757

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