SCYE1 antibody - N-terminal region (ARP40551_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

Gene Aliases

P43, HLD3, EMAP2, SCYE1, EMAPII

Gene ID

9255

Swiss Prot

Q12904

Accession Number

NP_004748

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SCYE1

Target

SCYE1 is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells.The protein encoded by this gene is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells.

Partner Proteins

AIMP2; TSNAX; UBC; CCAR2; RPL36; EEF1E1; IQGAP1; VARS; RPLP0; RPL27A; RPL23A; RPL21; RPL17; RPL15; RPL13; RPL7A; RARS; QARS; PTBP1; PSMC6; MARS; KARS; IARS; DNAJA1; EIF4G1; EIF2S3; EIF2S1; DARS; PAN2; gag; HSP90B1; MAPK8; LARS; EPRS; APP; COPS5; CUL1; PSM

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPF

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol