HNRNPU antibody - C-terminal region (ARP40518_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

Gene Aliases

SAFA, DEE54, HNRPU, SAF-A, U21.1, pp120, EIEE54, GRIP120, hnRNP U, HNRNPU-AS1

Gene ID

3192

Swiss Prot

Q00839

Accession Number

NP_114032

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human HNRNPU

Target

HNRNPU belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. HNRNPU contains a RNA binding domain and scaffold-associated region (SAR) -specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. But this cleavage does not affect the function of the encoded protein in RNA metabolism.

Partner Proteins

FBXW11; FUS; HUWE1; BTRC; UBC; TUBG1; TP53; AURKA; MAGED2; TUBGCP3; CEP57; AURKB; SUMO2; SUMO3; CEP70; CEP76; MDM2; LGALS3BP; EMD; HAUS2; TUBGCP4; CEP250; NEDD1; STAU1; IVNS1ABP; LGR4; ERG; RPA3; RPA2; RPA1; WWOX; RNF2; SHFM1; EED; rev; RPS29; RPS27; RPS6

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQF

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol