SNRPB Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Small nuclear ribonucleoprotein polypeptides B and B1

Gene Aliases

COD, CCMS, SNRPB1, SmB/B', Sm-B/B', snRNP-B, SmB/SmB'

Gene ID

6628

Swiss Prot

Q66K91

Accession Number

NP_003082

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SNRPB

Target

SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs) . These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs) . These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.

Partner Proteins

RFX6; KRT40; L3MBTL3; GOLGA2; DAB1; TRIM23; CEP55; BANP; SS18L1; TFIP11; RBPMS; CD2BP2; CALCOCO2; HUWE1; PNMA1; PSMA3; UBC; LIN28A; MEPCE; RPA3; RPA2; RPA1; SF3A3; NCS1; CDKN2A; SRPK3; PRPF4B; SRPK2; SKIV2L; ICAM1; CD81; IGSF8; PAN2; Snrpc; LSM8; SNRPD3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMP

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

24kDa

Protein Length

231

NCBI Gene Symbol

SNRPB

Host or Source

Rabbit

Protein Name

Small nuclear ribonucleoprotein-associated protein PIRNR PIRNR037187

Gene Name URL

SNRPB

Nucleotide Accession Number

NM_003091

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