NCBP1 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Nuclear cap binding protein subunit 1, 80kDa

Gene Aliases

NCBP, Sto1, CBP80

Gene ID

4686

Swiss Prot

Q09161

Accession Number

NP_002477

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NCBP1

Target

NCBP1 is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

POLDIP3; HUWE1; EIF4G1; UPF3B; EIF3B; MTOR; RPS6KB1; ALYREF; DDX39B; THOC3; THOC2; IVNS1ABP; UBC; LIN28B; LIN28A; ZNF346; SUMO1; SUZ12; EED; RNF2; BMI1; VAT1; MVP; TTC1; PPM1G; SERPINE2; NCL; NAP1L4; GFPT1; GARS; PUS1; TARDBP; YWHAE; RUVBL1; MPG; FN1; C17

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SRRRHSDENDGGQPHKRRKTSDANETEDHLESLICKVGEKSACSLESNLE

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol