ANP32A antibody - N-terminal region (ARP40204_T100)

Product Specifications

CAS Number

9007-83-4

Gene Name

Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A

Gene Aliases

LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1

Gene ID

8125

Swiss Prot

P39687

Accession Number

NP_006296

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ANP32A

Target

ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.

Partner Proteins

UBC; rev; PDLIM5; PLIN3; ARPC1B; OXSR1; EIF4A3; VBP1; TPD52L2; SSB; SRP14; RPA2; PKM; BAG1; SOX2; PCBP1; ESR1; THRB; PPARG; PGR; KPNA6; KPNA5; KPNA1; SUMO2; CHAF1A; HIST1H4A; HIST1H3A; HIST2H2BE; HIST2H2AC; SET; MEPCE; ELAVL1; ADAP1; NSFL1C; HSPB3; AXIN1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTI

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Pig: 93%; Rabbit: 93%; Rat: 86%; Sheep: 77%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

29kDa

Protein Length

249

NCBI Gene Symbol

ANP32A

Host or Source

Rabbit

Protein Name

Acidic leucine-rich nuclear phosphoprotein 32 family member A

Gene Name URL

ANP32A

Nucleotide Accession Number

NM_006305

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