PRMT2 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Protein arginine methyltransferase 2

Gene Aliases

HRMT1L1

Gene ID

3275

Swiss Prot

P55345

Accession Number

NP_001526

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PRMT2

Target

The protein arginine methyltransferases (PRMTs) include a family of proteins with related putative methyltransferase domains that modify chromatin and regulate cellular transcription. PRMT2 inhibits NF-kappaB-dependent transcription and promotes apoptosis and it exerts this effect by blocking nuclear export of IkappaB-alpha through a leptomycin-sensitive pathway, increasing nuclear IkappaB-alpha and decreasing NF-kappaB DNA binding. PRMT2 also rendered cells susceptible to apoptosis by cytokines or cytotoxic drugs, likely due to its effects on NF-kappaB.

Partner Proteins

FIP1L1; SPAG8; RIPK2; BAG6; RB1; HNRNPA1; E2F1; UBC; PSMB3; HHV8GK18_gp81; CPSF7; DMRTB1; HNRNPUL1; PRMT2; THRB; PGR; NCOA6; NCOA1; ESR2; RXRA; PRRC2A; ESR1; PPARG; RARA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILIL

Applications

IHC, WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

48kDa

Protein Length

433

NCBI Gene Symbol

PRMT2

Host or Source

Rabbit

Protein Name

Protein arginine N-methyltransferase 2

Gene Name URL

PRMT2

Nucleotide Accession Number

NM_001535

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

STJ190514 200 µl

Anti-ADA33 antibody

Ask

View Details

MBS9015808 Inquire

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MTR4 Polyclonal Antibody

Ask

View Details

46469051 1.0 mL

TEC Adenovirus (Human)

Ask

View Details

TBZ1537 unit

Korberin A

Ask

View Details

CBP1721-01 1 mg

TAU Blocking Peptide

Ask

View Details

CBP1721-02 5 mg

TAU Blocking Peptide

Ask

View Details