INSIG2 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Insulin induced gene 2

Gene Aliases

INSIG-2

Gene ID

51141

Swiss Prot

Q9Y5U4

Accession Number

NP_057217

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human INSIG2

Target

INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

RNF5; HMGCR; SCAP; SREBF1; RNF139; UBQLN1; UBQLN2; FAF2; ADRM1; PSMD14; BAG6; VCP; UBC; RPN1; PSMD13; PSMD12; PSMD11; PSMD4; PSMC6; PSMC5; PSMC3; PSMC2; PSMB3; PSMB1; PSMA7; PSMA2; LGALS7; JUP; INSIG1; HSPA8; HSPA6; HSPA5; HSPA1A; ENO1; DSP; AMFR; SREBF2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MAEGETESPGPKKCGPYISSVTSQSVNLMIRGVVLFFIGVFLALVLNLLQ

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 92%; Goat: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 92%; Rabbit: 100%; Rat: 92%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

25kDa

Protein Length

225

NCBI Gene Symbol

INSIG2

Host or Source

Rabbit

Protein Name

Insulin-induced gene 2 protein

Gene Name URL

INSIG2

Nucleotide Accession Number

NM_016133

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP1-28225MFV450 0.1 mL

Mouse Monoclonal CD3 epsilon Antibody (PPT3) [mFluor Violet 450 SE]

Ask

View Details

NBP2-92395-0.02mL 0.02 mL

Rabbit Polyclonal ASPM Antibody

Ask

View Details

JOT-EK0573Ra 96 wells

Rat acidic isoferritin, AIF ELISA KIT

Ask

View Details

MBS7076241-01 0.02 mg (E-Coli)

Recombinant Staphylococcus aureus Uncharacterized protein SAUSA300_2562 (SAUSA300_2562)

Ask

View Details

MBS7076241-02 0.1 mg (E-Coli)

Recombinant Staphylococcus aureus Uncharacterized protein SAUSA300_2562 (SAUSA300_2562)

Ask

View Details

MBS7076241-03 0.02 mg (Yeast)

Recombinant Staphylococcus aureus Uncharacterized protein SAUSA300_2562 (SAUSA300_2562)

Ask

View Details