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L3MBTL2 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

L (3) mbt-like 2 (Drosophila)

Gene Aliases

L3MBT, H-l (3) mbt-l

Gene ID

83746

Swiss Prot

Q969R5

Accession Number

NP_113676

Reactivity

Human, Cow, Dog, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human L3MBTL2

Target

L3MBTL2 contains 1 FCS-type zinc finger and 4 MBT repeats. It is putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.

Partner Proteins

TRIM42; STAC3; PHF10; TBC1D9B; PAICS; AES; SUMO2; SUMO1; PIAS1; HIST1H4A; HIST1H3A; RNF2; MPP3; PCGF6; RYBP; YAF2; SMARCAD1; HIST4H4; CBX3; HIST3H3; E2F6; Lin54; HDAC3; MEAF6; STAM2; RB1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVEN

Applications

WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 85%; Dog: 85%; Horse: 85%; Human: 100%; Pig: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

79kDa

Protein Length

705

NCBI Gene Symbol

L3MBTL2

Host or Source

Rabbit

Protein Name

Lethal (3) malignant brain tumor-like protein 2

Gene Name URL

L3MBTL2

Nucleotide Accession Number

NM_031488

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