ARC Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Activity-regulated cytoskeleton-associated protein
Gene Aliases
HArc, Arg3.1
Gene ID
23237
Swiss Prot
Q7LC44
Accession Number
NP_056008
Reactivity
Human, Guinea Pig
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human ARC
Target
ARC is required for consolidation of synaptic plasticity as well as formation of long-term memory. It regulates endocytosis of AMPA receptors in response to synaptic activity. It is required for homeostatic synaptic scaling of AMPA receptors. ARC plays a role in the regulation of cell morphology and cytoskeletal organization and is required in the stress fiber dynamics and cell migration.
Partner Proteins
UBE3A; UBC; KRT15
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
RHPLPKTLEQLIQRGMEVQDDLEQAAEPAGPHLPVEDEAETLTPAPNSES
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Guinea Pig: 86%; Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
43kDa
Protein Length
396
NCBI Gene Symbol
ARC
Host or Source
Rabbit
Protein Name
Activity-regulated cytoskeleton-associated protein
Gene Name URL
ARC
Nucleotide Accession Number
NM_015193
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