NR2E3 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Nuclear receptor subfamily 2, group E, member 3

Gene Aliases

PNR, RNR, rd7, ESCS, RP37

Gene ID

10002

Swiss Prot

Q9Y5X4

Accession Number

NP_055064

Reactivity

Human, Mouse, Rat, Cow, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NR2E3

Target

NR2E3 is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. NR2E3 is a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome.This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Partner Proteins

BCL11A; SIN3A; DHX30; TBL3; MYBBP1A; NCOR1; HDAC3; RBL1; RBBP7; RBBP4; HDAC1; CDK9; VDR; DEDD2; RBFOX2; IRF9; ZNF232; SNAPC1; PPARG; HOXC13; NR3C1; ELAVL2; POLR3D; RARA; NR1D1; CRX; RXRB; RXRA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVC

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 86%; Human: 100%; Mouse: 93%; Pig: 79%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

45kDa

Protein Length

410

NCBI Gene Symbol

NR2E3

Host or Source

Rabbit

Protein Name

Photoreceptor-specific nuclear receptor

Gene Name URL

NR2E3

Nucleotide Accession Number

NM_014249

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

CF503407 100 µg

Apc2 (ANAPC2) Mouse Monoclonal Antibody [Clone ID: OTI1H8]

Ask

View Details

133289-ML550 100 µL

SH2D2A (SH2 Domain-containing Protein 2A, SH2 Domain-containing Adapter Protein, T Cell-specific Adapter Protein, TSAd, VEGF Receptor-associated Protein, SCAP, TSAD, VRAP) (MaxLight 550)

Ask

View Details

abx265027-01 5 mg

[Lys1015,1024]-Thrombospondin-1 Peptide

Ask

View Details

abx265027-02 10 mg

[Lys1015,1024]-Thrombospondin-1 Peptide

Ask

View Details

abx265027-03 25 mg

[Lys1015,1024]-Thrombospondin-1 Peptide

Ask

View Details

MP215984 200 Reactions

Sstr2 Mouse qPCR Primer Pair (NM_001042606)

Ask

View Details