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NFATC2 antibody - C-terminal region (ARP38988_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

Gene Aliases

NFAT1, NFATP

Gene ID

4773

Swiss Prot

Q13469

Accession Number

NP_775114

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human NFATC2

Target

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR) . This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

GNB2; USP22; UBC; TNPO1; CSE1L; LRRK2; IQGAP1; PPP2R1A; JUN; NFATC2; CREBBP; IRF2BP2; TFAP4; HNRNPA1; TAF9; TUBA1A; KPNB1; SUV39H1; MAPK9; MAPK8; MED31; NFATC2IP; EP300; IRF4; PPP3R1; YWHAZ; PIN1; MEF2D; FOXP3; VIM; PRKCZ; YWHAQ; EGR4; EGR1; PPP3CB

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNLDQTYLDDVNE

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

100kDa

Protein Length

925

NCBI Gene Symbol

NFATC2

Host or Source

Rabbit

Protein Name

Nuclear factor of activated T-cells, cytoplasmic 2

Gene Name URL

NFATC2

Nucleotide Accession Number

NM_173091

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