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CORO1A Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Coronin, actin binding protein, 1A

Gene Aliases

P57, IMD8, TACO, CLABP, HCORO1, CLIPINA

Gene ID

11151

Swiss Prot

Q2YD73

Accession Number

NP_009005

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CORO1A

Target

CORO1A is a novel actin-binding protein with a WD repeat and a leucine zipper motif. CORO1A forms homodimers, that the association is mediated by the leucine zipper structure in the C-terminal region, and that it plays a role in the cross-linking of F-actin in the cell. The leukocyte plasma membrane associates with the actin cytoskeleton through CORO1A.Downregulation of CORO1A gene transcription restricts entry/survival of mycobacteria within macrophages

Partner Proteins

FSD2; GOLGA2; UBC; YTHDC1; SPATA20; POT1; TAB1; GIT2; POLR1C; STAT3; SMARCD1; MAGOH; SMAD3; LMO2; FHL3; FMNL1; NCF4; THBS1; ACTB; DKK1; UBE2G2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALI

Applications

WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

51kDa

Protein Length

461

NCBI Gene Symbol

CORO1A

Host or Source

Rabbit

Protein Name

Coronin-1A

Gene Name URL

CORO1A

Nucleotide Accession Number

NM_007074

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