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LZTR1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Leucine-zipper-like transcription regulator 1

Gene Aliases

NS2, NS10, BTBD29, LZTR-1, SWNTS2

Gene ID

8216

Swiss Prot

Q8N653

Accession Number

NP_006758

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human LZTR1

Target

Leucine-zipper-like transcriptional regulator 1 (LZTR1) is belived to be a DNA-binding protein and transcriptional regulator based on its predicted structural characteristics. The transcript is present in several essential fetal organs and is hemizygously deleted in some DiGeorge syndrome patients. LZTR1 is thought to play a critical role in embryogenesis.This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.

Partner Proteins

LZTR1; TUBGCP4; CUL3; UBC; CNOT6L; ZNF584; ZNF714; ASB12; FANK1; TRIM5; KDM2B; L3MBTL3; POLR1B; ANKRD53; EHMT1; E2F8; PAPOLG; ZNF490; SND1; AATF; ZNF451; ZZZ3; SCMH1; ZBTB1; WWP1; RAI1; CEBPZ; SUGP2; NR1H3; CHAF1A; MED16; HDAC4; MED7; RUVBL1; IKBKG; ZNF17

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

AGPGSTGGQIGAAALAGGARSKVAPSVDFDHSCSDSVEYLTLNFGPFETV

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

95kDa

Protein Length

840

NCBI Gene Symbol

LZTR1

Host or Source

Rabbit

Protein Name

Leucine-zipper-like transcriptional regulator 1

Gene Name URL

LZTR1

Nucleotide Accession Number

NM_006767

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