HIC1 antibody - middle region (ARP38806_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Hypermethylated in cancer 1
Gene Aliases
Hic-1, ZBTB29, ZNF901
Gene ID
3090
Swiss Prot
Q14526
Accession Number
NP_006488
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human HIC1
Target
HIC1 is a transcriptional repressor. HIC1 may act as a tumor suppressor. HIC1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIC1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.
Partner Proteins
PIAS4; PIAS3; PIAS2; SP1; STAT3; SIRT1; MTA1; UBE2I; SUMO2; HIC2; TCF4; CTBP2; CTBP1; EED; PHF1; EZH2; PHF19; SUZ12; UBC; MBD3; RBBP4; CHD3; SENP3; HDAC4; PIAS1; ARID1A; HIC1; HDAC1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
GETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGE
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
74kDa
Protein Length
714
NCBI Gene Symbol
HIC1
Host or Source
Rabbit
Protein Name
Hypermethylated in cancer 1 protein
Gene Name URL
HIC1
Nucleotide Accession Number
NM_006497
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