MEF2D Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Myocyte enhancer factor 2D

Gene Aliases

DKFZp686I1536

Gene ID

4209

Swiss Prot

Q14814

Accession Number

NP_005911

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MEF2D

Target

MEF2D is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. MEF2D mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival.MEF2D plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription.MEF2D plays a critical role in the regulation of neuronal apoptosis.

Partner Proteins

SUMO1; CDK6; ASCL1; APP; SUMO2; UBC; CABIN1; MEF2A; HDAC1; HIRA; ASH2L; KMT2D; RBBP5; MEN1; PRKACA; SENP3; HDAC4; COPS5; CARM1; PRMT5; KAT2B; HDAC3; SNCA; MAPK14; HDAC5; EP300; MAPK7; CASP7; MEF2D; MEF2C; NFATC2; SP1; YWHAQ

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLD

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

56kDa

Protein Length

521

NCBI Gene Symbol

MEF2D

Host or Source

Rabbit

Protein Name

Myocyte-specific enhancer factor 2D

Gene Name URL

MEF2D

Nucleotide Accession Number

NM_005920

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