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CEBPZ Antibody-N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

CCAAT enhancer binding protein zeta

Gene Aliases

CBF, CBF2, NOC1, HSP-CBF

Gene ID

10153

Swiss Prot

Q03701

Accession Number

NP_005751

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPZ

Target

This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurance of acute myeloid leukemia (AML) .

Partner Proteins

UBC; TARBP2; EED; RNF2; HDAC11; SIRT7; SUMO2; RELA; RPS6KA6; LAMTOR3; PRKRA; UBE3A; HMOX2; GSK3B; ZBTB7B; LZTR1; STAT6; RXRG; PCBD1; TP73; TP53; NFYB; LAG3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MAAVKEPLEFHAKRPWRPEEAVEDPDEEDEDNTSEAENGFSLEEVLRLGG

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 77%; Horse: 80%; Human: 100%; Mouse: 80%; Pig: 77%; Rabbit: 85%; Rat: 82%; Yeast: 83%; Zebrafish: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

115 kDa

Protein Length

1054

NCBI Gene Symbol

CEBPZ

Host or Source

Rabbit

Protein Name

CCAAT/enhancer-binding protein zeta

Gene Name URL

CEBPZ

Nucleotide Accession Number

NM_005760.3

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