CBFA2T3 Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Core-binding factor, runt domain, alpha subunit 2; translocated to, 3
Gene Aliases
ETO2, MTG16, MTGR2, ZMYND4, RUNX1T3
Gene ID
863
Swiss Prot
O75107
Accession Number
BAA31276
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human CBFA2T3
Target
The t (16;21) (q24; q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
Partner Proteins
Zbtb38; Zbtb4; ZBTB33; GMEB2; SEC24A; MATN2; ZBTB47; UBC; RUNX1; TAL1; TRIM33; SIN3B; NCOR1; HDAC3; CBFA2T3; CBFA2T2; HDAC1; PRKAR2A; RUNX1T1; LDB1; TCF3; HDAC8; HDAC6; HDAC2
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
MPASRLRDRAASSASGSTCGSMSQTHPVLESGLLASAGCSAPRGPRKGGP
Applications
WB
Purification
Protein A purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1.0 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
60kDa
Protein Length
545
NCBI Gene Symbol
CBFA2T3
Host or Source
Rabbit
Protein Name
Protein CBFA2T3
Gene Name URL
CBFA2T3
Nucleotide Accession Number
NM_005187
Curated Selection
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