CIR Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Corepressor interacting with RBPJ, 1
Gene Aliases
CIR
Gene ID
9541
Swiss Prot
Q86X95
Accession Number
NP_004873
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CIR
Target
CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC) . CIR is also required for RBPSUH-mediated repression of transcription.
Partner Proteins
CEP76; NEK6; U2AF1; SRSF2; SRSF1; RP9; HDAC2; SAP30; SNW1; TCEA1; NCOR2; RBPJ
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
RSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPG
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
52kDa
Protein Length
450
NCBI Gene Symbol
CIR1
Host or Source
Rabbit
Protein Name
Corepressor interacting with RBPJ 1
Gene Name URL
CIR1
Nucleotide Accession Number
NM_004882
Curated Selection
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