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EZH2 (ARP38470_P050)

Product Specifications

Gene Name

Enhancer of zeste homolog 2 (Drosophila)

Gene Aliases

WVS, ENX1, KMT6, WVS2, ENX-1, EZH2b, KMT6A

Gene ID

2146

Swiss Prot

Q15910

Accession Number

NP_004447.2

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EZH2

Target

EZH2 is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems.

Partner Proteins

FBXW11; CEP63; HOTAIR; EED; BRCA1; SUZ12; SNAI1; SRSF1; SDCBP; UPF1; RBBP7; RBBP4; RAP1GAP; PLEC; PKM; POTEE; DHX36; AEBP2; HIST4H4; KLC4; SERPINB12; PHF5A; FIP1L1; FBXL18; CPSF7; DDX3X; DBN1; SLC25A10; COPB1; CALML3; ATP5C1; ATP5B; ATP2A2; ARG1; AR; ANXA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQE

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

85kDa

Specificity

From peptide immunogen, will recognize all 5 isoforms.

Protein Length

751

NCBI Gene Symbol

EZH2

Host or Source

Rabbit

Protein Name

Histone-lysine N-methyltransferase EZH2

Gene Name URL

EZH2

Nucleotide Accession Number

NM_001203247

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